Khoom Txheej Txheem
Kev faib tawm: GLP -1 Tam sim no Receptor Egonist (GLP {1} .
Lub Hom Phiaj: glucagon-zoo li peptide -1 (GLP -1) receptor .
Semaglutide yog GLP -1 Tam sim no tau sim los ntawm tib neeg txoj hnyuv, thiab ua tiav peb lub luag haujlwm tseem ceeb:
- Ntshav Qab Zib Txo
Los ntawm kev ua kom zoo siab GLP -1 Cov khoom siv tsis zoo, nws muaj kev pheej hmoo ntawm hypoglycemia) thiab inhibits glucagon decition .
Haum rau Hom 2 Ntshav Qab Zib Hom 2 (T2Dm), tshwj xeeb tshaj yog rau cov rog lossis cov neeg mob plawv high-{3}}
- Lub cev yuag
Qeeb lub plab zom mov, nce kev kub ntxhov siab, thiab txo qis qab qabteite .
WeGovey® (2 {{{{}} 4 mg / lub lim tiam) yog kev pom zoo rau cov neeg rog (BMI ntau dua lossis sib luag rau 27) cov neeg mob nrog cov teeb meem.
- Kev Tiv Thaiv Kev Tiv Thaiv Cardiovascular
Txo cov kev pheej hmoo ntawm cov xwm txheej tseem ceeb (MACE) (xws li kev mob stroke), kev ywj pheej ntawm cov txiaj ntsig qis (nejm, 2016).
Nws yog cov tshuab uas ua semaglutide poob siab dua los ua qhov hnyav ntawm cov neeg mob hnyav tuaj yeem ua rau muaj qhov hnyav, thiab cov neeg mob ntshav qab zib} Cov neeg mob ntshav qab zib tuaj yeem poob tau 6g.
Qhov ncauj vs txhaj
Muaj ob txoj kev loj ntawm semaglutide:
Kev txhaj tshuaj tiv thaiv (subcutaneous, ib zaug ib lim piam)
Ntsiav tshuaj (ib zaug txhua hnub)
Kev zoo tshwj xeeb ntawm qhov ncauj semaglutide
- Tsis yog tus thawj coj tsis yog tus neeg mob, tus neeg mob ua tau zoo dua;
Zam kev txhaj tshuaj tiv thaiv tsis xis nyob (mob, cov tshuaj tiv thaiv hauv zos) thiab kev pheej hmoo} thiab haum rau cov neeg mob uas noj tshuaj ntevthiab muaj kev puas siab puas ntsws kom txhaj tshuaj .
- Kev hloov kho cov tshuaj yooj yim
Tsis xav tau rau tub yees (kev txhaj tshuaj yuav tsum tau muab khaws cia ntawm 2-8 qib yuav muab khaws cia ntawm chav tsev kub tom qab qhib) {{1}.
Haum rau kev mus ncig lossis tawm .
- Tsim nyog rau kev tswj ntshav qab zib thaum ntxov
Kev tswj hwm qis (3mg / 7mg) tuaj yeem siv rau cov ntshav qab zib ua ntej lossis mob ntshav qab zib me ntsis, thaum muaj feem ntau yog siv rau mob hnyav rau cov neeg mob hnyav.
Cov kev mob tshwm sim ntau
- Kev tiv thaiv lub plab zom mov
xeev siab, ntuav, raws plab (feem ntau tshwm sim nyob rau hauv thaum ntxov ntawm cov tshuaj noj, thiab maj mam unceviate raws li lub cev yoog) .
- Muaj peev xwm txaus ntshai
Cov kev sim tsiaj qhia tias nws yuav nce cov qog qog ntshav (nws tsis meej hauv tib neeg);
Qee tus txiv neej yuav ntsib kev ua kom tsis ua hauj lwm zoo .